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03 July 2012 - Adrian to chair a symposium at Serotonin Club meeting

Adrian Newman-Tancredi Ph.D. will be chairing a symposium at the forthcoming Serotonin Club meeting in Montpellier (10-12th June 2012). The symposium will present recent advances in the brain-region-selective targeting of serotonergic mechanisms. In particular, the symposium will be relevant to the identification of drugs that preferentially elicit responses in those brain regions that mediate therapeutic actions whilst avoiding effects on brain regions that may control side-effects.

Adrian will present the emerging concept of "biased agonism" and its relevance to serotonin 5-HT1A receptors. Adrian has extensive experience of serotonin receptor pharmacology and drug discovery and has presented to a wide variety of audiences. If you would like more information about Adrian's lectures: Contact.


3.00-5.00 PM Theatrum anatomicum, Symposium 11.

“From ligand functional selectively to brain region selectivity: Differential pharmacological targeting of serotonin system.”

Chair: Adrian Newman-Tancredi : NeuroAct Communication, Castres, France
Co-Chair: Umberto Spampinato, Université Victor Segalen Bordeaux2, Centre Recherche Inserm U862, Bordeaux, France

1. “Biased agonism at serotonin 5-HT1A receptors : Preferential postsynaptic activity for improved therapy of CNS disorders.”
Adrian Newman-Tancredi, NeuroAct Communication, Castres, France

2. “Agonist-directed signaling at 5-HT2A receptors in cortex.”
Laura M. Bohn, The Scripps Reseach Institute, Jupiter, USA

3. “Central 5-HT2B receptors exert a differential control of mesocorticolimbic and nigrostriatal dopamine pathway activity: An in vivo microdialysis study in the rat.”
Umberto Spampinato, Université Victor Seglan Bordeaux2, Centre Recherche Inserm U862, Bordeaux, France

4. “Characterization of serotonin neurons in the Raphe based on molecular and electrophysiological identity.”
Sebastian Fernandez, INSERM, Paris, France (NIDA Travel Awardee)

For full details of this year's Serotonin Club meeting click here.