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[3H](+)S 14297: a novel, selective radioligand at cloned human dopamine D3 receptors.

Newman-Tancredi A, Audinot V, Jacques V, Peglion JL, Millan MJ.
Neuropharmacology. 1995 Dec;34(12):1693-6.

The selective dopamine D3 receptor antagonist [3H](+)S 14297 ((+)-[7-(N,N-dipropylamino)-5,6,7,8-tetrahydro-naphtho(2,3b)dihydro,2,3- furane]), labelled to high specific activity (145 Ci/mmol), bound to cloned human dopamine D3 receptors but displayed negligible binding to cloned human D2 receptors. [3H](+)S 14297 exhibited rapid association and dissociation, high affinity saturable binding (Kd = 7.0 nM) and a competition binding profile highly correlated with that of [125I]iodosulpride (r = 0.98).